Tissue Engineering
Entwicklung und Kultivierung von Geweben
5 CPSummerEN
Prerequisites
Recommended, as written
Basic knowledge in cell biology
Contents
• Basic organisation of tissues: Cells and extracellular matrix (ECM) • ECM: Molecular structure & function • Cell-ECM Interaction • Cell-Cell interactions • Cellular Development and Fate Decisions (Proliferation, migration, determination, differentiation, cell-cell & cell-matrix interaction, apoptosis) • Cells Sources for Tissue Engineering: stem cells, differentiated cells from adult tissues, problem of donor-recipient cell transfer • Wound healing as a Natural Model of "Tissue Engineering": Inflammation, tissue formation, tissue remodelling • Cell based therapies: Principles and Applications • 3D Cell Cultures Systems: Principles and Applications
Learning outcomes
• Explain and apply fundamental scientific principles as well as advanced, specialized knowledge in tissue engineering and regenerative medicine. • Describe the basic structure of tissues and analyze interactions between cells and the extracellular matrix. • Explain key developmental processes in mammals and relate them to tissue engineering strategies. • Identify and explain the core components of tissue engineering, including cells, signaling molecules, biomaterials, bioreactors, and three-dimensional (3D) cell culture systems. • Distinguish between different cell-based therapies and evaluate their roles as therapeutic concepts in regenerative medicine. • Analyze and discuss 3D cell culture approaches and evaluate their relevance for tissue engineering, disease modeling, toxicology and pharmacology and translational research. • Develop independent ideas and concepts for solving scientific problems related to tissue engineering.
Assessment
Written Examination (120 min)
Literature (7)
- Molecular Biology of The Cell, Alberts et al., 5th/6th edition, Garland Sciences, 2008/2015
- Cell and Molecular Biology. Concepts and experiments. Karp G., John Wiley & Sons, 2008
- Principles of Tissue Engineering, Lanza R. P. et al., Academic Press, 2nd edition 2000
- Methods of Tissue Engineering, Anthony Atala, Robert P. Lanza (eds.), Academic Press, New York, 2002
- Tissue Engineering, Clemens van Blitterswijk (senior editor), Elsevier, Amsterdan,Boston, Heidelberg, … (2008)
- Functional Tissue Engineering, Farshid Guilak, David L. Butler, Steven A. Goldstein, David Mooney, C. MacLachlan, Springer, New York, Berlin, 2003
- Specific original scientific publications
Source: BTU's module description · retrieved 28 Sep 2026Original